Optima AUC 分析型超速离心机

Optima AUC 搭载两个无缝集成的光学检测系统：吸光度检测模块（ABS），用于检测溶液中 170-800 nm 紫外可见光吸收分析物以及瑞利（Rayleigh）干涉光检测模块（INT），用于监测检测样品和参比溶液之间的沉降差异。Optima AUC 凭借其独特的光学检测系统与物理沉降特性，支持用户精准表征蛋白质和核酸复合物以及无光吸收特性的颗粒，例如碳水化合物和脂质体。了解有关分析型超速离心技术的更多信息，请 访问专门页面 。

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Optima AUC 分析型超速离心机

功能特点

提高数据质量

  • 径向分辨率更高
  • 信噪比优于 ProteomeLab
  • 干涉光学系统的垂直像素增加 11 倍
  • 能够在短时间内对多达 20 个离散波长的复杂系统进行精准分析

在自然无基质条件下分析各种粒子，包括：

  • 蛋白质、肽、抗体
  • 脂质纳米颗粒、脂质体和微胶粒
  • 聚合物
  • 微胶粒
  • 脂质体
  • 细胞外囊泡
  • 偶联药物
  • 病毒载体和病毒样颗粒
  • 纳米颗粒

相较于其他任何类似技术，所提供数据能够揭示更多核心与关键问题，包括：

  • 沉降和扩散系数
  • 化学计量/寡聚状态
  • 异质性
  • 分子间可逆和不可逆相互作用
  • 自聚集
  • 样品纯度
  • 形状和粒径
  • 质量
  • 配方/稳定性研究

操作便捷

  • 远程监控功支持您随时随地轻松进行仪器设置、实时监控并获取所需数据
  • 内置可切换的光学检测模块，可加快工作流程准备工作并有效避免对光学系统造成损坏
  • 兼容多种 ProteomeLab 样品池和转头
  • 用户友好触摸屏，直观展示实验设计的实时进展

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选择 Optima AUC 型号

Learn more on the Optima AUC Analytical Ultracentrifuge

 

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Addressing the Challenges of Purification & Quality Control in Gene Therapy Our panelists will focus on several pertinent topics in rAAV process development including current challenges, technologies for overcoming quality control hurdles, best practices for downstream processing, as well as discuss the current trends and future outlook of this rapidly growing therapeutic frontier.
Characterization of LNPs via Density Matching AUC
Optima AUC Overview, New Analytical Ultracentrifuge A brief overview of some of the features of the Optima AUC analytical ultracentrifuge that make it the most robust research technology available for thorough analysis of proteins, viruses and other macromolecules in their native, matrix-free state
Introduction to AUC - an Analytical Ultracentrifuge A brief but informative visual demonstration of the process of analytical ultracentrifugation, which enables live monitoring of macromolecules in solution under native, biologically relevant conditions
The History of AUC - An Analytical Ultracentrifuge A brief review of highlights in the long history of analytical ultracentrifugation -- from the 1920s through the dawn of the 21st century -- focused on its importance in the fields of science, medicine and industry

Analytical Ultracentrifugation: A Versatile and Valuable Technique for Macromolecular Characterization

 

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Analytical Ultracentrifugation: Analyzing Sedimentation and Diffusion for Enhanced Molecular Characterization

 

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Quantifying crude AAV Samples using DGE-AUC

 

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Applications of ultracentrifugation in purification and characterization of biomolecules

 

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