Optima AUC 分析型超速离心机

Optima AUC 搭载两个无缝集成的光学检测系统:吸光度检测模块(ABS),用于检测溶液中 170-800 nm 紫外可见光吸收分析物以及瑞利(Rayleigh)干涉光检测模块(INT),用于监测检测样品和参比溶液之间的沉降差异。Optima AUC 凭借其独特的光学检测系统与物理沉降特性,支持用户精准表征蛋白质和核酸复合物以及无光吸收特性的颗粒,例如碳水化合物和脂质体。了解有关分析型超速离心技术的更多信息,请 访问专门页面

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功能特点

提高数据质量

  • 径向分辨率更高
  • 信噪比优于 ProteomeLab
  • 干涉光学系统的垂直像素增加 11 倍
  • 能够在短时间内对多达 20 个离散波长的复杂系统进行精准分析

在自然无基质条件下分析各种粒子,包括:

  • 蛋白质、肽、抗体
  • 脂质纳米颗粒、脂质体和微胶粒
  • 聚合物
  • 微胶粒
  • 脂质体
  • 细胞外囊泡
  • 偶联药物
  • 病毒载体和病毒样颗粒
  • 纳米颗粒

相较于其他任何类似技术,所提供数据能够揭示更多核心与关键问题,包括:

  • 沉降和扩散系数
  • 化学计量/寡聚状态
  • 异质性
  • 分子间可逆和不可逆相互作用
  • 自聚集
  • 样品纯度
  • 形状和粒径
  • 质量
  • 配方/稳定性研究

操作便捷

  • 远程监控功支持您随时随地轻松进行仪器设置、实时监控并获取所需数据
  • 内置可切换的光学检测模块,可加快工作流程准备工作并有效避免对光学系统造成损坏
  • 兼容多种 ProteomeLab 样品池和转头
  • 用户友好触摸屏,直观展示实验设计的实时进展

选择 Optima AUC 型号

Learn more on the Optima AUC Analytical Ultracentrifuge

 

Content and Resources

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Resource Type
Looking Under the Hood: Getting Started with the Optima AUC In the webinar we discuss the fundamentals of analytical ultracentrifugation and look at a few sample applications.
Webinar: An Intro to Characterization of Biomolecules Using AUC Analytical Ultracentrifugation (AUC) is one of the most powerful biophysical tools used today for the characterization of biological samples ranging from small drug molecules to intact viruses, vesicles and microparticles
Gene Therapy Workflow from Production to Quality Control Watch the video or read on to learn more about some of the instruments used in the gene therapy workflow.
Characterizing Viral Vector Fullness in Density Gradient Separations Known as density gradient equilibrium analytical ultracentrifugation (DGE-AUC), it’s a simplified method that provides high-resolution benefits along with numerous advantages over the current gold standard sedimentation velocity AUC. Watch webinar to learn more.

Analytical Ultracentrifugation: A Versatile and Valuable Technique for Macromolecular Characterization

 

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Analytical Ultracentrifugation: Analyzing Sedimentation and Diffusion for Enhanced Molecular Characterization

 

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Quantifying crude AAV Samples using DGE-AUC

 

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Applications of ultracentrifugation in purification and characterization of biomolecules

 

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教程

 

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技术文件

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