分析型超速离心机
溶液中的大分子表征
分析型超速离心机技术是测定蛋白质或其他大分子的分子量、流体力学和热力学性质的最通用、最严格和最准确的方法。贝克曼库尔特生命科学分析型超速离心机提供高效优异的超速离心性能，能快速提供用于确定基础蛋白质研究中蛋白质分子量的数据，助力学术和生物制药研究。
FAQ on Analytical Ultracentrifuges
What is analytical ultracentrifugation?
Analytical ultracentrifugation (AUC) is a solution-based analytical technique that uses high centrifugal forces to study the physical properties of macromolecules and particles. Researchers use AUC to determine molecular weight, size distribution, shape, aggregation state, and molecular interactions without the need for labels or reference standards.
How does analytical ultracentrifugation work?
Analytical ultracentrifugation works by spinning samples at very high speeds and monitoring how molecules move through a solution. The rate of sedimentation is measured using optical detection systems, allowing researchers to characterize molecular size, shape, concentration, and interaction behavior with high precision.
What is the difference between analytical and preparative ultracentrifugation?
Preparative ultracentrifugation is primarily used to separate and isolate particles for collection, while analytical ultracentrifugation is used to characterize and measure molecular properties. Analytical systems provide quantitative information about molecular weight, sedimentation behavior, aggregation, and sample heterogeneity.
What are the applications of analytical ultracentrifugation?
Analytical ultracentrifugation is widely used in biopharmaceutical development, protein analysis, antibody characterization, viral vector research, nanoparticle studies, and formulation development. It is particularly valuable for studying biomolecules under conditions that closely resemble their native environment.
