免疫疗法

免疫疗法涉及理解和利用免疫系统和癌细胞之间的关系,以对抗肿瘤发生。有许多不同的潜在免疫治疗方法,包括基于细胞的策略,如过继细胞转移、受体通路策略(如检查点抑制)和基于主体的方法,如抗体治疗。基因工程可以被纳入所有这些方法。基因编辑可用于调节受体表达水平、诱导特定分子的产生、改变细胞表型或改变免疫反应的整体强度。

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How can nanoparticles be used for immunotherapy? We examine how nanoparticles can be used for immunotherapy as well as in other research areas
How do oncolytic viruses target cancer cells in immunotherapy? We examine how oncolytic viruses target cancer cells in immunotherapy and how genetically modified viruses apply
Are there different CRISPR-associated system (Cas) proteins? Discussion around how different protein families associate with CRISPR (clustered regularly interspaced short palindromic repeats)
How is the CAR receptor introduced to the T cell? We explore how the CAR receptor is introduced to the T cell and the delivery methods that are involved
What antigens can a CAR-T cell target? Discussion around what antigens a CAR-T cell can target and for what purposes