Echo 650 Plus 系列主要特点与优势
主要特征
- 采用声学液体处理技术，通过声波实现液体转移，无需物理接触即可处理多种液体（包括 DMSO 体系）
- 实现高通量（最高约 700 次液滴/秒）高精度、高重复性的纳升级液体转移，最低转移体积2.5 nL
- 支持“任意源孔至任意目标孔”的复杂组合转移模式
- 从以下载体进行转移：384 孔及 1536 孔 Echo 认证微孔板和96 管阵列样品管*
- 支持向符合 ANSI / SLAS 标准的 96 / 384 / 1536孔板中转移液体（干板或预填充板）
- 支持样品及试剂的直接稀释
- 集成动态机器学习工具，可基于液体特性（如 DMSO 含水量）自动优化声学参数
- 可无缝集成其他液体处理系统或自动化平台
主要优势
- 减少样本损失、交叉污染、残留及浸出物风险
- 支持分析体系小型化，同时保持数据质量稳定
- 降低试剂消耗、减少塑料耗材及危险液体使用，并节约珍贵样本资源
- 自动生成剂量反应曲线及标准曲线，并减少传统吸头移液及连续稀释可能引入的误差
- 加速复杂多组分实验及分析流程执行
- 实现从样本存储到检测板准备的全流程非接触自动化液体处理
- 在使用声学样品管*时，支持超高密度样本存储，保持样本完整性，并可快速调用目标样本进行筛选
*仅适用于支持样品管功能的型号
Echo 650 Plus 系列应用
Echo 650 Plus 系列声学液体处理系统主要应用于医药与生物技术研发领域，应用包括但不限于：
- 高通量筛选（High-Throughput Screening ，HTS）
- 融合深度学习与湿实验的筛选流程（如OOD discovery）
- 样本管理
- 从合成到筛选流程（Synthesis-to-Screening ，S2S）
- 直接面向生物学（Direct -to-biology, D2B）
- 检测方法开发
- 组合/协同筛选
- 合并扰动
- 阵列功能基因组筛选（siRNA/sgRNA/RNP）
如未找到您需要的应用场景，可联系我们的专家.
Echo 650 Plus 系列核心升级
在 Echo 650 系列经过验证的性能基础上，Echo 650 Plus 系列声学液体处理系统带来了新的可靠性、稳定性和可用性：
下一代声能转换器（NGT）
新一代转换器，减少维护需求，保持稳定性能。设备在长期存储后，可在24小时内恢复运行。
下一代核心电子
实时计算速度显著提升，且功耗比传统 Echo 650 系列低 54%。从而提升系统整体性能、降低运营成本。
动态流体分析 2（DFA2）：新型DPA 和 DMA技术
基于机器学习的新型动态塑料分析（DPA） 和动态液丘分析（DMA） ，实现更准确、精密且一致的声学液滴喷射（ADE）。
*取决于板和校准
BeckmanConnect 远程支持工具
为我们的认证工程师提供安全远程访问，无需现场访问即可快速诊断、排查和解决系统问题。这一改进最大限度地减少了停机时间，加快了问题解决，并帮助提升实验室生产力。 了解更多 →
Echo 650 Plus 系列规格
| 移液精度 | 2.5 nL |
| 技术 | 声学液滴喷射技术（ADE）、动态流体分析 2（DFA2）及下一代换能器技术（NGT） |
| 通量 | 非常适合中高通量声学液体处理流程 |
| 液态校准 | 不需要 |
| 兼容来源耗材 |
Echo 认证 384 孔低死体积（384LDV）来源微孔板、 Echo 认证 384 孔聚丙烯（384PP）来源微孔板、 Echo 认证 1536 孔低死体积（1536LDV）来源微孔板、声学样品管* |
| 兼容目标耗材 | 兼容大多数符合 ANSI/SLAS 标准的 96 孔、384 孔及 1536 孔微孔板（高度 8–16 mm）。对于不符合该标准的实验耗材（如显微玻片），可在使用用户自备夹具的条件下实现适配。 |
| 兼容液体类型 | 兼容液体包括：基础缓冲溶液（如 PBS）、细胞培养基、含 DNA 的水溶液（剪切 DNA、cDNA、质粒、基因片段）、RNA（mRNA、gRNA、sgRNA）、蛋白质（酶、抗体）及 RNP 复合物、血清、血浆、含表面活性剂的水溶液及试剂、引物/探针、高达50% 甘油溶液、70–100% DMSO 溶液、晶体学试剂（MPD、PEG、渗透溶液）以及醇类溶液** |
| 软件配置 |
标配：Echo Client Utility 软件 可选：Echo 软件应用套件 1.8.X，包括： Plate Reformat、Cherry Pick、Dose-Response、 Combination Screen、Plate Audit、Array Maker |
| 电源要求 | 100–230 VAC, 5 A, 50/60 Hz |
| 环境温度范围 | 16°C– 26°C (61°F–79°F) |
| 环境湿度要求 | 10–80%（无冷凝条件） |
| 最大噪声水平 | 66 dBA |
| 设备尺寸 | 宽度：53.8厘米（21.2英寸） 深度：74.6厘米（29.3英寸） 高度：91.5厘米（36.0英寸） |
| 真空需求 |
方案一：实验室集中真空系统，最低 200 Torr（266 mbar） 方案二：独立真空系统（含 10 L 缓冲罐），最低泵速 2.0 m³/小时，最低压力 100 Torr |
| 最大使用海拔 | 最高可达2000米（6562英尺） |
| 重量 | 117公斤（258磅） |
| 客户端 PC 操作系统 | Windows® 11 |
| 运行模式 | 可独立运行或集成至自动化系统运行 |
*声学样品管仅适用于 Echo 650T Plus 及 Echo 655T Plus 型号；Echo 650 Plus 和 Echo 655 Plus 型号可通过升级实现该功能。
**液体兼容性可能因来源微孔板类型、样品粘度、溶质浓度及声学特性等因素而发生变化。
工作流程自动化集成系统
为满足广泛的样品通量需求，Echo 650 Plus 系列液体处理机无缝集成高度可配置的Access Laboratory工作站 和 Access单/双机器人系统 ，支持多种设备，实现全自动化工作流程。
- 专为样本管理和筛选工作流实现最佳通量设计
- 紧凑且符合人体工学的设计，配备对接模块、转盘、可伸缩搁板和柜门
- 可选功能包括 HEPA 或环境控制模块，防止样品污染、水化或蒸发
Echo 650 Plus 系列服务支持
Echo 650 Plus 系列专为性能设计，您的服务计划确保您的投资得到保护，最大化运行时间，使您的工作流程持续前进。通过 Beckman Coulter 生命科学的服务计划，您将获得：
- 认证 OEM 零部件
- 专家工程师支持
- 优先响应
- 软件和硬件更新
- 可预测的成本控制
- 全面的远程及现场支持
- OEM 合规
需要更多信息？请访问我们的 服务计划网页了解更多信息。
立即询价
Echo Qualified Consumables Compatible with Echo 650 Plus Series
Echo® Qualified 384-Well Polypropylene Microplate, Clear, Non-sterile
Echo® Qulified 384-Well Polypropylene (PP) Source Microplates ensure accurate and precise transfer with the Echo® Liquid Handler. This microplate is highly rsistant to solvents including DMSO and buffers making it ideal for compound and sample storage.
Echo® Qualified 384-Well Polypropylene Microplate, Clear, Sterile
Echo® Qulified 384-Well Polypropylene (PP) Source Microplates ensure accurate and precise transfer with the Echo® Liquid Handler. This microplate is highly rsistant to solvents including DMSO and buffers making it ideal for compound and sample storage.
Echo(R) Qualified 384-Well Polypropylene Microplate, Clear, Non-sterile, Barcoded
Echo® Qulified 384-Well Polypropylene (PP) Source Microplates ensure accurate and precise transfer with the Echo® Liquid Handler. This microplate is highly rsistant to solvents including DMSO and buffers making it ideal for compound and sample storage.
Echo® Qualified 384-well Cyclic Olefin Copolymer (COC) Source Microplate, Low Dead Volume, Clear, Non-sterile
Echo® Qualified 384-Well Low Dead Volume (LDV) Source Microplates are designed to minimize dead volume when using the Echo® Liquid Handler. This microplate is constructed of Cyclic Olefin Copolymer (COC) for optimal acoustic transfer performanceand DMSO storage. Each lot of microplates is tested and certified to meet stringent performance specifications.
The 384-Well Low Dead Volume (LDV) plate is designed to minimize dead volume when using the Echo® liquid handling system. This microplate is constructed of Cyclic Olefin Copolymer (COC) for optimal acoustic transfer performance and DMSO storage. Each lot of microplates is tested and certified to meet stringent performance specifications. Additional benefits of the microplate include: compatibility with heat sealing devices, designed for barcode customization and optimized for robotic handling.
Precise Manufacturing for Superior Results
For best results, Echo Liquid Handlers are designed to use Echo Qualified 384-well and 1536-well Source Microplates for precise and accurate liquid transfer.
Echo Qualified Microplates deliver the best possible results in compound storage and miniaturized assays, and each plate is insured to meet the specifications required for consistent acoustic transfers. Labcyte performs functional qualification tests on each microplate lot with an Echo Liquid Handler to verify that our microplates deliver superior precision and accuracy and DMSO hydration measurements.
Echo® Qualified 384-well Cyclic Olefin Copolymer (COC) Source Microplate, Low Dead Volume, Clear, Sterile
Echo® Qualified 384-Well Low Dead Volume (LDV) Source Microplates are designed to minimize dead volume when using the Echo® Liquid Handler. This microplate is constructed of Cyclic Olefin Copolymer (COC) for optimal acoustic transfer performanceand DMSO storage. Each lot of microplates is tested and certified to meet stringent performance specifications.
The 384-Well Low Dead Volume (LDV) plate is designed to minimize dead volume when using the Echo® liquid handling system. This microplate is constructed of Cyclic Olefin Copolymer (COC) for optimal acoustic transfer performance and DMSO storage. Each lot of microplates is tested and certified to meet stringent performance specifications. Additional benefits of the microplate include: compatibility with heat sealing devices, designed for barcode customization and optimized for robotic handling.
Precise Manufacturing for Superior Results
For best results, Echo Liquid Handlers are designed to use Echo Qualified 384-well and 1536-well Source Microplates for precise and accurate liquid transfer.
Echo Qualified Microplates deliver the best possible results in compound storage and miniaturized assays, and each plate is insured to meet the specifications required for consistent acoustic transfers. Labcyte performs functional qualification tests on each microplate lot with an Echo Liquid Handler to verify that our microplates deliver superior precision and accuracy and DMSO hydration measurements.
Echo(R) Qualified 384-well Cyclic Olefin Copolymer (COC) Source Microplate, Low Dead Volume, Clear, Non-sterile, Barcoded
Echo® Qualified 384-Well Low Dead Volume (LDV) Source Microplates are designed to minimize dead volume when using the Echo® Liquid Handler. This microplate is constructed of Cyclic Olefin Copolymer (COC) for optimal acoustic transfer performanceand DMSO storage. Each lot of microplates is tested and certified to meet stringent performance specifications.
The 384-Well Low Dead Volume (LDV) plate is designed to minimize dead volume when using the Echo® liquid handling system. This microplate is constructed of Cyclic Olefin Copolymer (COC) for optimal acoustic transfer performance and DMSO storage. Each lot of microplates is tested and certified to meet stringent performance specifications. Additional benefits of the microplate include: compatibility with heat sealing devices, designed for barcode customization and optimized for robotic handling.
Precise Manufacturing for Superior Results
For best results, Echo Liquid Handlers are designed to use Echo Qualified 384-well and 1536-well Source Microplates for precise and accurate liquid transfer.
Echo Qualified Microplates deliver the best possible results in compound storage and miniaturized assays, and each plate is insured to meet the specifications required for consistent acoustic transfers. Labcyte performs functional qualification tests on each microplate lot with an Echo Liquid Handler to verify that our microplates deliver superior precision and accuracy and DMSO hydration measurements.
Echo® Qualified 1536-well Cyclic Olefin Copolymer (COC) Source Microplate, Low Dead Volume, Clear, Non-sterile
The 1536-Well Low Dead Volume (LDV) plate
improves assay results by increasing working range
and reducing dead volume. This microplate is
constructed with exceptional bottom flatness and
of Cyclic Olefin Copolymer (COC), which provides
optical clarity and improved signal levels for
luminescence and flourescence-based assays. Each
lot of plates is tested and certified to meet stringent
performance specifications to ensure lot to lot
consistency
Echo® Qualified 1536-well Cyclic Olefin Copolymer (COC) Source Microplate, Low Dead Volume, Clear, Sterile
The 1536-Well Low Dead Volume (LDV) plate
improves assay results by increasing working range
and reducing dead volume. This microplate is
constructed with exceptional bottom flatness and
of Cyclic Olefin Copolymer (COC), which provides
optical clarity and improved signal levels for
luminescence and flourescence-based assays. Each
lot of plates is tested and certified to meet stringent
performance specifications to ensure lot to lot
consistency
Echo(R) Qualified 1536-well Cyclic Olefin Copolymer (COC) Source Microplate, Low Dead Volume, Clear, Non-sterile, Barcoded
The 1536-Well Low Dead Volume (LDV) plate
improves assay results by increasing working range
and reducing dead volume. This microplate is
constructed with exceptional bottom flatness and
of Cyclic Olefin Copolymer (COC), which provides
optical clarity and improved signal levels for
luminescence and flourescence-based assays. Each
lot of plates is tested and certified to meet stringent
performance specifications to ensure lot to lot
consistency
MicroClime® Environmental Lid
The MicroClime® Environmental Lid minimizes edge
effects and preserves the concentrations of solutions
in microplate wells. The MicroClime® Environmental
Lid incorporates a unique, fluid-absorbing matrix
that creates a vapor barrier, protecting the sample
from the exterior environment from evaporation or
hydration and greatly reducing edge effects. The
MicroClime Environmental Lid does not require any
specialized tools and is compatible with robotic plate
lidding and delidding systems.
Increase Microplate Efficiency Up to 37%
MicroClime Lids enable you to use all the wells in your microplate, from edge to center. This can increase your microplate productivity by up to 37%. They also eliminate damaging edge effects which may occur due to long-term cell incubation. They are compatible with a wide variety of SBS-standard microplates.
Minimize edge effects and preserves the concentrations of solutions in microplate wells. MicroClime Lids incorporate a unique, fluid-absorbing matrix. The absorbed fluid creates a vapor barrier that protects the sample from the exterior environment, especially near the edges of the microplate. Compatible with robotic plate lidding systems, and they can be filled with a variety of fluids, using either a hand-held syringe or automated bulk fillers.
MicroClime® Environmental Lid, Sterile
The MicroClime® Environmental Lid minimizes edge
effects and preserves the concentrations of solutions
in microplate wells. The MicroClime® Environmental
Lid incorporates a unique, fluid-absorbing matrix
that creates a vapor barrier, protecting the sample
from the exterior environment from evaporation or
hydration and greatly reducing edge effects. The
MicroClime Environmental Lid does not require any
specialized tools and is compatible with robotic plate
lidding and delidding systems.
Increase Microplate Efficiency Up to 37%
MicroClime Lids enable you to use all the wells in your microplate, from edge to center. This can increase your microplate productivity by up to 37%. They also eliminate damaging edge effects which may occur due to long-term cell incubation. They are compatible with a wide variety of SBS-standard microplates.
Minimize edge effects and preserves the concentrations of solutions in microplate wells. MicroClime Lids incorporate a unique, fluid-absorbing matrix. The absorbed fluid creates a vapor barrier that protects the sample from the exterior environment, especially near the edges of the microplate. Compatible with robotic plate lidding systems, and they can be filled with a variety of fluids, using either a hand-held syringe or automated bulk fillers.
MicroClime® Environmental Lid, Introductory Pack of 10 lids
The MicroClime® Environmental Lid minimizes edge
effects and preserves the concentrations of solutions
in microplate wells. The MicroClime® Environmental
Lid incorporates a unique, fluid-absorbing matrix
that creates a vapor barrier, protecting the sample
from the exterior environment from evaporation or
hydration and greatly reducing edge effects. The
MicroClime Environmental Lid does not require any
specialized tools and is compatible with robotic plate
lidding and delidding systems.
Increase Microplate Efficiency Up to 37%
MicroClime Lids enable you to use all the wells in your microplate, from edge to center. This can increase your microplate productivity by up to 37%. They also eliminate damaging edge effects which may occur due to long-term cell incubation. They are compatible with a wide variety of SBS-standard microplates.
Minimize edge effects and preserves the concentrations of solutions in microplate wells. MicroClime Lids incorporate a unique, fluid-absorbing matrix. The absorbed fluid creates a vapor barrier that protects the sample from the exterior environment, especially near the edges of the microplate. Compatible with robotic plate lidding systems, and they can be filled with a variety of fluids, using either a hand-held syringe or automated bulk fillers.
MicroClime® Environmental Lid, Sterile, Introductory Pack of 10 lids
The MicroClime® Environmental Lid minimizes edge
effects and preserves the concentrations of solutions
in microplate wells. The MicroClime® Environmental
Lid incorporates a unique, fluid-absorbing matrix
that creates a vapor barrier, protecting the sample
from the exterior environment from evaporation or
hydration and greatly reducing edge effects. The
MicroClime Environmental Lid does not require any
specialized tools and is compatible with robotic plate
lidding and delidding systems.
Increase Microplate Efficiency Up to 37%
MicroClime Lids enable you to use all the wells in your microplate, from edge to center. This can increase your microplate productivity by up to 37%. They also eliminate damaging edge effects which may occur due to long-term cell incubation. They are compatible with a wide variety of SBS-standard microplates.
Minimize edge effects and preserves the concentrations of solutions in microplate wells. MicroClime Lids incorporate a unique, fluid-absorbing matrix. The absorbed fluid creates a vapor barrier that protects the sample from the exterior environment, especially near the edges of the microplate. Compatible with robotic plate lidding systems, and they can be filled with a variety of fluids, using either a hand-held syringe or automated bulk fillers.
Echo Software Applications
Frequently Used With
Access整合系统
贝克曼库尔特生命科学Access双机器人实验自动化系统是一个紧凑、模块化、高效率和高通量的平台,经过设计和优化,可在样品管理工作流中使用Echo声波移液系统.该实验自动化系统将行业领先的设备和软件与人体工程学和环境管理选项结合在一起,以提供完整、易于使用的、存储到测定的样品管理解决方案.
Access自动化台面整合系统
Access台面操作自动化系统整合革命性声波移液系统Echo、自动板处理系统和其他三方设备,为广泛应用量身定制的无人值守的自动化系统.Access自动化台面整合系统是模块化、灵活的解决方案,可在需要时轻松扩展.
技术文件
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ECHO is a trademark or registered trademark of Labcyte Inc. in the United States and other countries. Labcyte is a Beckman Coulter company. All other trademarks are the property of their respective owners.
