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IVD-R Annex I Global Safety and Performances Requirements (GSPR). A New Set of Requirements for Clinical Laboratories Performing Laboratory Developed Tests
Liquid Biopsy Cancer Biomarkers – Current Status, Future Directions We will discuss the current state of liquid biopsy, with a particular focus on cancer genomics. We also discuss some of the keys to success in working with cell-free DNA (cfDNA), and we will finish with future directions of this exciting field.
Analyzing Biological Systems with Flow Cytometry Accurately measuring biological parameters in heterogeneous cell populations, such as tissue samples, can be a challenge. When researchers use traditional bulk methods to analyze their cell samples, they obtain a single readout representing an average over all cells. There is no way to know if a signal came from low to moderate expression of the target throughout the entire population or from a few cells with high expression. Additionally, more abundant cell subpopulations dilute fainter signals. Therefore, bulk cell analyses mask rare phenotypes and events in heterogenous populations
AUC Insights - Assessing the quality of adeno-associated virus gene therapy vectors by sedimentation velocity analysis Since the first gene therapy study in the late 1980s, there has been an ongoing interest in gene therapy strategies.
AUC Insights - Analysis of Protein-Protein-Interactions by Analytical Ultracentrifugation Protein-Protein-Interactions (PPI) are fundamental to the function of proteins and the life of a cell. PPIs can be divided into homo- or heterocomplexes whether being present as dimers or multimers

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