CD305-PE, NKTA255, 50 tests, RUO

CD305, also called LAIR1 (Leucocyte-associated Ig-like receptor 1), is a 31 kDa type 1 transmembrane molecule with a single N-terminal extracellular Ig superfamily C2 domain. The extracellular domain contains one N-glycosylation site. CD305 is expressed on the majority of lymphocytes, NK cells, monocytes, dendritic cells, and naïve B cells. It inhibits cell cytotoxicity, cell activation, proliferation, and differentiation by phosphorylation of its cytoplasmic ITIM motifs.