Engineered for high-performance workflows, the kits support rare mutation detection, small RNA profiling and multimodal analysis

INDIANAPOLIS – (April 8, 2026) – Beckman Coulter Life Sciences—a Danaher business and a global leader in research laboratory instruments, automation and genomic solutions—announces expanded distribution of Apostle MiniMax® High-Efficiency Isolation Kits for cfDNA, cfRNA and total cfNA extraction. Developed by Apostle Inc., these kits are now available globally through Beckman Coulter Life Sciences commercial channels.

This offering builds on the companies’ established partnership, in which Beckman Coulter Life Sciences first introduced the Apostle MiniMax® High Efficiency Cell-Free DNA Isolation Kit through a distribution agreement. The collaboration pairs Apostle’s proprietary magnetic nanoparticle technology with Beckman Coulter Life Sciences global reach, liquid handling automation and expertise in supporting high-throughput genomic workflows.

“We’ve long invested in genomic solutions that reduce complexity and improve productivity,” says Sudharshana Seshadri, Vice President, Product Management. “With broader access to Apostle MiniMax® extraction kits—adding cfRNA and total cfNA solutions to the cfDNA kit already offered—laboratories can achieve high-yield purification for liquid biopsy workflows from limited samples and maintain confidence in downstream NGS and PCR applications.”

The Apostle MiniMax® portfolio delivers dedicated solutions for cfDNA, cfRNA, and total cfNA extraction. With Beckman Coulter Life Sciences now offering the cfRNA and total cfNA kits alongside the existing cfDNA product, the full portfolio addresses key challenges in liquid biopsy workflows, including recovering highly fragmented cfDNA, isolating fragile small RNAs, and enabling multimodal analysis from limited samples. Each kit is designed to produce clean, high-yield, high-quality cell-free nucleic acids for NGS and PCR applications.

“As a field application specialist, I am in firsthand contact with our customers. We are seeing interest in cfRNA/cfNA extractions from labs that have been using cfDNA analyses. This follows a trend that we’ve previously experienced with FFPE samples in tumor characterization, where it has now become standard to analyze RNA and DNA from the same sample," says Milan Dieris, Field Application Specialist.

Learn more about Apostle MiniMax® Kits at beckman.com/reagents/genomic/cell-free-dna-rna-extraction-kits.

Products and applications are not intended or validated for use in diagnostic procedures.

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About Beckman Coulter Life Sciences

Time is the most critical facet in the laboratory today: time to get life-saving therapies to patients faster; reclaiming time by automating tedious manual workflows; and saving time otherwise spent addressing erroneous or complex results.

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About Danaher

Danaher is a leading global life sciences and diagnostics innovator, committed to accelerating the power of science and technology to improve human health. Our businesses partner closely with customers to solve many of the most important health challenges impacting patients around the world. Danaher's advanced science and technology - and proven ability to innovate - help enable faster, more accurate diagnoses and help reduce the time and cost needed to sustainably discover, develop and deliver life-changing therapies. Focused on scientific excellence, innovation and continuous improvement, our approximately 63,000 associates worldwide help ensure that Danaher is improving quality of life for billions of people today, while setting the foundation for a healthier, more sustainable tomorrow. Explore more at www.danaher.com.

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