BioLector XT微型生物反应器与 Biomek i5 自动化工作站整合系统

BioLector XT 高通量微型生物反应器与 Biomek i5 自动化工作站整合系统，助您实现在线培养监测和培养基制备的全过程自动化。独创的微生物培养自动筛选平台，支持生物信号实时跟踪，提高实验结果可重复性，助您轻松设计并开展高度精确实验。基于 BioLector XT 微型生物反应器的在线实时信号（如生物量、pH 值、溶解氧浓度、实验时间、荧光信号等），系统可单独触发取样、加样操作（如添加诱导剂或补料溶液）或接种，而无需暂停振摇。

  • 在线测量生物量、pH 值、溶解氧（DO）和荧光信号等关键培养参数
  • 增加无人值守时间
  • 自动化功能显著减少潜在污染
  • 实验结果可放大至台式生物发酵罐
  • 实现结果可重复性和可放大性
     

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资源 + 工具
BioLector学习中心 微型生物反应器耗材 Biomek i-Series 学习中心 视频中心
BioLector XT微型生物反应器与 Biomek i5 自动化工作站整合系统

BioLector XT 微型生物反应器与 Biomek i5 自动化工作站整合系统

全流程自动化

该系统可将BioLector XT的实时信号用作孔独立的工作站移液操作的触发信号进行自动抽取样品、添加培养基和诱导剂溶液及接种，增加无人值守时间，并确保同等高质量结果输出。

实现可重复性与可放大性

整合系统可全面优化您的工作流程，并获得可重复性实验数据。可放大的实验结果将助您将更多产品加速推向市场。

强大的软件支持

培养模式与在线触发信号（BioLector XT 微型生物反应器实时检测信号）全面结合，助您实现 24/7 全天候连续运行。

大幅降低污染风险

系统在运行期间，自动清洗并消毒 Biomek 固定吸头，大幅减少样品间交叉污染的可能性。

 

Content and Resources

Automating Cell Line Development for Biologics Cell line development is a highly-involved, multi-week workflow that involves the plating, screening, and expansion of single cell-derived clones to establish a protein-expression cell line. This complex process required significant throughput of sterile cell manipulations, long-term incubations, centrifugation, cell counting, monoclonality determination and growth tracking, and protein production assessment.
Biomek i–Series Automated Illumina® TruSight Tumor 170 32 Sample Method We demonstrate the automated performance of Illumina TruSight Tumor 170 32 Sample Method on the Biomek i5 Span–8 Genomics Workstation.
High throughput cultivation of the cellulolytic fungus Trichoderma reesei in the BioLector® In this application note we show, that the BioLector&reg; system is suitable for high throughput fermentation of <em>T. reesei</em> while maintaining essentially the same morphology, cellulase production and growth kinetics as in conventional shake flask fermentations. Furthermore, we demonstrate different application examples that take advantage of the optical online measurement capabilities of the BioLector&reg;.
Highly Reproducible Automated Proteomics Sample Preparation on Biomek i-Series Protein digestion and analysis by mass spectrometry is an essential process in numerous proteomic approaches such as biomarker discovery. However, the sample preparation can be tedious and error prone. Automation can relieve the burden of sample preparation while also reducing the variability between users and across experiments.
E. coli fed-batch cultivation using the BioLector® Pro This technical note gives an overall understanding of the use of the BioLector<sup>&reg;</sup> Pro on the example of a standard <em>Escherichia coli</em> fed-batch cultivation experiment with one-sided pH-control. Standard experiment conditions are indicated and the standard protocol settings of the BioLection software are shown. Furthermore, the data analysis of the experiment is presented.