Automated Gibson SOLA® Enzymatic DNA Synthesis

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Telesis Bio + Beckman Coulter Life Sciences: A Breakthrough Collaboration

Telesis Bio and Beckman Coulter Life Sciences have united to redefine the landscape of synthetic biology. By integrating the Gibson SOLA® Enzymatic DNA Synthesis Platform with the Biomek Echo One Gene Synthesis Automation System, this collaboration delivers on-premises, high-fidelity, and scalable DNA synthesis. We empower researchers to innovate faster, more sustainably, and with greater control, transforming your workflow from design to synthesis.

Achieve More with Gibson SOLA® Synthesis and Biomek Echo One Automation

Discover the power of this integrated solution:

Flexible, High-Fidelity, Rapid DNA Synthesis

Achieve unmatched accuracy and reproducibility in your workflows with on-demand DNA synthesis in a day. Choose how to build your DNA with Intelligent Synthesis to achieve the greatest degree of efficiency.

Fully Automated, Scalable Workflows

Automate every step from design to synthesis using the Biomek Echo One Gene Synthesis System, featuring the robust Biomek i7 Hybrid Workstation and the precise Echo 525 Liquid Handler.

Non-Toxic, Sustainable Chemistry

Replace hazardous reagents with aqueous, environmentally friendly solutions, promoting a safer lab.

Protect Critical Sequence Information

Keep your IP secure with on-premises sequence design software and DNA synthesis workflows.

The Gibson SOLA® Platform: Your Digital-to-Biological Converter

Unlike traditional phosphoramidite or TDT synthesis, the Gibson SOLA® Platform uses an innovative hybridization-based, block assembly method that fundamentally changes the way you synthesize DNA.

With Gibson SOLA®, you can:

  • Produce 10s to 100s of kb of high-quality DNA.
  • Reduce synthesis time from weeks to under 24 hours.
  • Eliminate the need for dedicated, costly HPLC columns.
  • Enable on-demand, in-house production of DNA directly in your lab.
  • Achieve high-fidelity plasmid synthesis with >95% error-free clones.
Telesis Bio Gibson SOLA Platform Infographic

Biomek Echo One System: Automation Engineered for Synthesis

The Biomek Echo One Gene Synthesis Solution is specifically designed to automate the Gibson SOLA® workflow efficiently and reliably. It integrates industry-leading technology to provide walk-away capability and precision.

Featuring:

Echo 525 Acoustic Liquid Handler

Echo 525 Acoustic Liquid Handler

Delivers non-contact, nanoliter-scale dispensing critical for rapid pooling and normalization steps, ensuring accuracy without tip-based errors

Biomek i7 Hybrid Workstation

Provides full walk-away automation capacity, integrating advanced pipetting, thermal cycling, incubation, and automated labware handling

Intelligent Software Control (SAMI)

The powerful SAMI EX software orchestrates complex workflows, enabling streamlined method execution and flexible customization via features like:

  • Guided Labware Setup (GLS): Simplifies deck setup and reduces errors
  • DeckOptix Final Check (DFC): Visually confirms deck layout before runs
  • Method Options Selector (MOS): Allows easy customization of protocols for specific needs

Voices from the Collaboration

We are setting a new standard for on-premises biofoundries.
— Eric Esser, CEO, Telesis Bio

This innovation brings exciting new possibilities to DNA synthesis workflows, empowering researchers to push the boundaries of scientific discovery.
— Ewan Grant, Senior Director, Beckman Coulter Life Sciences

Applications Powered by Gibson SOLA® Enzymatic DNA Synthesis

This powerful integrated solution unlocks new potential across a range of critical research areas:

Antibody icon red

Antibody Drug Discovery

Cell and Gene Tehrapy icon red

Cell & Gene Therapy

Vaccine and Therapeutic Development icon red

Vaccine & Therapeutic Development

Precision Medicine icon red

Precision Medicine

Genome Editing icon red

Genome Editing

Insightful Resources

Telesis Bio Gibson SOLA® Platform Automated on the Biomek Echo One Gene Synthesis Solution for Accelerating Therapeutic Discovery - App Note Front Page

Application note
Telesis Bio Gibson SOLA® Platform Automated on the Biomek Echo One Gene Synthesis Solution for Accelerating Therapeutic Discovery

 

Automating the Future of Synthetic Biology - Telesis Bio + Beckman Coulter Life Sciences Collaboration Flyer Front Page

Flyer
Telesis Bio + Beckman Coulter Life Sciences: A Breakthrough Collaboration in DNA Synthesis

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Any methods or applications illustrated are for demonstration only and are not validated by Beckman Coulter. Beckman Coulter makes no warranties of any kind whatsoever express or implied, with respect to these protocols, including but not limited to warranties of fitness for a particular purpose or merchantability or that the protocol is non-infringing. All warranties are expressly disclaimed. Your use of these methods are solely at your own risk, without recourse to Beckman Coulter. Not intended or validated for use in the diagnosis of disease or other conditions.

Products are not intended or validated for use in the diagnosis of disease or other conditions.
ECHO is a trademark or registered trademark of Labcyte Inc. in the United States and other countries. Labcyte is a Beckman Coulter company. All other product names and brands are properties of their respective owners.