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Please enjoy centrifugation tips and insights from experts at Beckman Coulter Life Sciences.

application note ELEVATING EV Characterization with Analytical Ultracentrifugation (AUC)

Elevating EV Characterization with Analytical Ultracentrifugation

EVs are an exciting area of research. Nonetheless, characterizing EVs remains a challenge due to their inherent heterogeneity.
DGUC reveals the nature of heterogeneity in multiple LNP formulations

DGUC and Lipid Nanoparticles

Density gradient ultracentrifugation can be used to purify fractions of loaded lipid nanoparticles.
When should I choose centrifugation instead of affinity chromatography for purifying viral vectors?

DGUC vs AC

Density Gradient Ultracentrifugation is advantaged over affinity chromatography for viral vector purification.
Why should I choose ultracentrifugation as the preferred method for extracellular vesicle purification?

High-Purity EV isolation

Ultracentrifugation (UC) is broadly considered the gold standard for EV purification due to its capacity to reproducibly isolate specific subpopulations of EVs.
An introduction to the Optima Analytical Ultracentrifuge

Cell Culture Optimization using data from AUC

Discover how data from AUC can help improve AAV Production Yield.

Multiwavelength AUC characterization & QC

Discover how data from AUC determines dose optimization in therapeutic liposomes.
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Why use AUC?

Getting comfortable with Analytical Ultracentrifugation.
Can Sapphire windows be used for low-UV AUC experiments?

Sapphire vs. Quartz

Sapphire windows provide better data than quartz windows for high speed AUC applications, such as peptides and small molecules.
How can I prepare consistent density gradients for reproducibly purifying samples via ultracentrifugation?

Density Gradient Ultracentrifugation (DGUC)

How can I prepare consistent density gradients for reproducibly purifying samples via ultracentrifugation?
AUC provides high-resolution data on AAV particle quality & fullness

AAV Analysis with AUC

AUC provides high-resolution data on AAV particle quality & fullness.
Discover the ways to transfer an existing centrifugation protocol to a new rotor, bottle, or tube.

Seamless Protocol Transfer

Discover the ways to transfer an existing centrifugation protocol to a new rotor, bottle, or tube. 
Optima AUC analytical ultracentrifuge Time-saving Features Improve Efficiency

Optima AUC Advantages

Discover the advantages of using the Optima AUC to improve your data quality and workflow efficiency.
Discover the difference between sterile and certified free consumables for centrifugation

Consumable Purity Grades

Discover the difference between sterile and certified free consumables, then determine the necessary purity grade for your application.

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